Diseases caused by dengue virus denv are a major public health problem worldwide, considered one of the infections with more prevalence in tropical and subtropical zones of the world. Mosquitoborne dengue fever threat spreading in the americas dengue or breakbone fever is a mosquitoborne disease that may worsen with global warming. Dengue fever is an infectious disease carried by mosquitoes and caused by any of four related dengue viruses. Dengue virus is an important arboviral infection that is the cause of an important mosquitoborne infectious disease dengue infection. Dengue fever this article was prepared to provide more. Dengue fever this article was prepared to provide more information about dengue fever and dengue hemorrhagic fever dengue fever warning an april 2011 news article cautioned that the medical sciences national institute of health had warned that this years weather changes could lead to an outbreak of dengue fever.
Current and historical conditions indexed list of current and historical nationally notifiable conditions. On september 26, 2012, a woman aged 35 years from kosrae in the federated states of micronesia fsm was hospitalized with fever, headache, muscle pain, vomiting, leukopenia, and thrombocytopenia. Jul 19, 20 dengue outbreak federated states of micronesia, 2012 20. Treatment for dengue and dengue hemorrhagic fever is supportive. Dengue epidemiologia, fisiopatologia, evolucao e tratamento. Dengue fever is a flulike syndrome, but severe dhf is characterized by coagulopathy and increased vascular fragility and permeability. Worldwide, the world health organization estimates that dengue is responsible for the hospitalization of approximately 500,000 individuals and the death of approximately 25,000 individuals each year. Genetically engineered mosquitoes resist spreading any form of. Longterm persistence of clinical symptoms in dengue. Admission criteria management of febrile phase the febrile phase of dengue illness, which usually lasts 57 days in most. We conducted a prospective cohort study from january 2010 to september 2012. Dengue fever df is the fastest emerging arboviral infection spread by aedes aegypti mosquitoes with major public health consequences for millions of people around the world, and in particular the southeast asia and asiapacific regions of the world health organization who. Dengue virus denv infection is prevalent across tropical regions and may cause severe disease. They are found virtually throughout the tropics fig fig1 1 and cause an estimated 50100 million illnesses annually, including 250 000500 000 cases of dengue haemorrhagic fevera severe manifestation of dengueand 24 000 deaths.
Travellers workers, tourists, migrants returning from countries. In the 20 dengue outbreak in singapore, a significant rise in the number of dengue fever cases was reported in singapore. Utility of warning signs in guiding admission and predicting. Dec 11, 2015 a total of 320 blood specimens collected between september 2011 and january 2012 were tested. During 2016 till november, a total number of 179 deaths due to dengue and no death due to chikungunya has been reported in the country. The dengue burden was highest at the citylevel with a maximum singleyear estimate of 560 dalys per million individuals for 2002. People get dengue from the bite of an infected mosquito. Dengue has claimed 179 lives across the country this year while no death has been reported due to chikungunya, though it affected 21,000 people, the rajya sabha was told today. They are found virtually throughout the tropics fig. Admission criteria management of febrile phase the febrile phase of dengue illness, which usually lasts 57 days in most cases, may be biphasic, with the temperature ranging between 390c and 400c. Phe publications gateway number 2014157 pdf, 112kb, 8 pages this file may not be suitable for users of assistive technology. Research open access is temperature the main cause of. It requires urgent hospitalization as it may even lead to death.
Dengue is a mosquitoborne viral disease endemic in tropical and subtropical countries that has emerged as a serious international public health threat with almost half of the worlds. Dengue is a vectorborne viral infection and a globally important public health problem. Epidemiologia sazonalidade dengue x precipitacao 17102017dengue9 fonte. Dengue fever is a virus transmitted to humans through bites from the aedes mosquito, a daybiting mosquito. Dengue outbreak federated states of micronesia, 201220. Over 80% of the dengue burden derived from dengue fever cases. Jun 29, 2002 dengue viruses, single stranded rna viruses of the family flaviviridae, are the most common cause of arboviral disease in the world.
Despite the intense research in the pathogenesis of denv, this feature is not well understood. According to the temperaturebased model dengue risk increased between the two decades, and epidemics of the last decade coincided with high annual risk. The mosquitoborne disease marked by fever, rash, and debilitating pain results from any of four genetically distinct versions of the dengue. Dengue fever and dengue hemorrhagic fever are viral diseases transmitted by aedes mosquitoes, usually aedes aegypti. Dengue viruses, single stranded rna viruses of the family flaviviridae, are the most common cause of arboviral disease in the world. This figure was far beyond the highest number of cases per week in the years 2010, 2011 and 2012. Oct 24, 20 the recommendation from the 2009 world health organization guidelines for managing dengue suggests that patients with any warning sign can be hospitalized for observation and management. Morfologia del dengue ensayos y trabajos cintyfigueroa1. The highest risk is associated with dhf that progresses to. Health experts have known about dengue fever for more than 200 years. The mosquito becomes infected when it bites a person who has dengue virus in their blood.
Costa, isabelle matos pinheiro and calado, daniela cristina. The recommendation from the 2009 world health organization guidelines for managing dengue suggests that patients with any warning sign can be hospitalized for observation and management. A global strategy on dengue fever and dhf was developed in 1995 and its implementation was bolstered in 1999. The figure above shows the number n 728 and rate of suspected dengue cases, by age group and rapid diagnostic test rdt result in kosrae state, federated states of micronesia during 2012. In the week of 1622 june 20, there was a record of 842 dengue cases in singapore in a single week. The use of ns1 rapid diagnostic test and qrtpcr to. One of the main target cells for denv infection is monocytes. Pdf on jan 1, 2012, andre ricardo ribas freitas and others published fisiopatologia y aspectos clinicos del dengue find, read and cite all the research you need on researchgate. The importance of accurate diagnosis of dengue fever. Research open access is temperature the main cause of dengue.
Epistaxe e gengivorragia nao sao comuns e a hemorragia gastrintestinal pode ser observada nos casos graves. This disease used to be called breakbone fever because it sometimes. We prospectively assessed the standard diagnostics korea bioline dengue duo denv rapid diagnostic test rdt to ns1 antigen and antidenv igm ns1 and igm in children in cambodia, with the aim of. Travellers workers, tourists, migrants returning from countries where diseases are endemic are increasingly introducing dengue and other vectorborne viruses into the who european region. Rapid diagnostic tests for dengue virus infection in febrile. A new who strategy for dengue control and prevention for the period 2012 20 is being implemented with the main aim to diminish dengue. Dengue fever df is the fastest emerging arboviral infection spread by aedes aegypti mosquitoes with major public health consequences for millions of people around the world, and in particular the south. Dengue, region 11, 20 texas department of state health.
This disease used to be called breakbone fever because it sometimes causes severe joint and muscle pain that feels like bones are breaking. Dengue fever in england, wales and northern ireland. A total of 320 blood specimens collected between september 2011 and january 2012 were tested. Irma perez contreras 1,2, juan ulises villanueva morales 2, miguel angel salinas paredes 2, miguel angel enriquez guerra 1,2, ricardo perez fuentes 2,3. The number of positive cases for dengue and chikungunya in the country during 2016 till november are 90,277 and 21,094 respectively, health minister j p nadda said in a written reply. Role of monocytes in the pathogenesis of dengue springerlink. Dengue hemorrhagic fever is characterized by high fever, bleeding and liver enlargement. It takes a week or more for the dengue virus to replicate in the mosquito. Dengue is an emerging vectorborne disease that is spread by the bite of aedes.
Dengue fever is common in tropical areas, so take extra precautions if you travel somewhere with this type of climate. Feb 24, 2015 dengue virus denv infection is prevalent across tropical regions and may cause severe disease. Dengue is a disease caused by any one of four closely related dengue viruses denv1, denv2, denv3, and denv4. Dengue claimed 179 lives, no death due to chikungunya. When the fever declines, symptoms including persistent. Cameron p simmons, in infectious diseases third edition, 2010. Dengue is among the most important mosquitoborne viral disease worldwide 1. Enhanced performance of an innovative dengue iggigm rapid. Worldwide, the world health organization estimates that dengue is. Research open access is temperature the main cause of dengue rise in nonendemic countries. Dengue prevention remains dependent upon control of the vector, although several vaccine candidates as well as new tools for vector elimination are under evaluation and will be introduced in the near future. Dengue is a febrile viral infection caused by four different viruses dengue virus serotypes 14 that are transmitted by aedes mosquitoes. Subsequently, the awareness of variable responses to the infection presenting.
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